Jing Liu a,Yeu-Ching Shi b,David Yue-Wei Lee a, *.Applications of Pueraria lobata in treating diabetics and reducing alcohol drinking[J].Chinese Herbal Medicines (CHM),2019,11(2):141-149
葛根在治疗糖尿病和戒酒中的应用
Applications of Pueraria lobata in treating diabetics and reducing alcohol drinking
  
DOI:10.1016/j.chmed.2019.04.004
中文关键词:  糖尿病  葛根  野葛  戒酒
英文关键词:diabetics  Pueraria lobata (Willd) Ohwi  reducing alcohol drinking
基金项目:
Author NameAffiliation
Jing Liu a a Bio-Organic and Natural Products Research Laboratory, Mailman Research Center, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA 
Yeu-Ching Shi b b Taiwan Indigena Botanica, Taipei 10684, China 
David Yue-Wei Lee a, * a Bio-Organic and Natural Products Research Laboratory, Mailman Research Center, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA 
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中文摘要:
      葛根(Pueraria lobata)是中国传统上最重要的药用植物之一。根据《伤寒论》(外感热病论)记载,传统上可用于解热、眼睛酸痛、口干及与高血压相关的头痛和颈部僵直等症状。20世纪70年代的研究表明,从葛根中提取的异黄酮是愈风宁心片主要的生物活性成分,可用于治疗中风后的患者。本文回顾了葛根在治疗糖尿病和戒酒方面的最新应用。由于葛根毒性较低,是用于开发治疗人类疾病的植物药的良好机遇。
英文摘要:
      Pueraria lobata is one of the most important medicinal herbs used traditionally in China. According to Shanghan Lun (Treatise on Exogenous Febrile Disease), it has been used traditionally to relieve body heat, eye soring, dry mouth, headache associated with high blood pressure, and stiff neck problems. Modern studies in the 1970s revealed that isoflavonoids extracted from P. lobata were the bioactive components of an herbal remedy namely Yufeng Ningxin Tablets for the treatment of patients after stroke. This article reviews recent application of P. lobota in the treatment of diabetics and in reducing alcohol drinking. In view of its low toxicity profile, P. lobota stands an excellent chance to be developed as a phytomedicine for treating human diseases.
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